Hypericum perforatum edo Santiago belarra depresio arin eta moderatua tratatzeko egokietsita dagoen landarea da, medikamentu eta elikagai osagarri moduan komertzializatuta dagoena. Eraginkortasun handia erakutsi du, alta, elkarrekintza ugari aurkezten ditu sendagai batzuekin batera hartzean. Eskuragarritasun erraza duenez, kontuan hartu beharreko arriskua da. Hori dela-eta, artikulu honek kontuan eduki beharreko elkarrekintzen ebidentzia zientifikoa biltzen du. Herritarrek ezagutu behar duten jazoera posible bat da, landare-jatorriko produktuak beti seguruak edo seguruagoak diren pertzepzio okerra baitute anitzek. Kontrol eta heziketan medikuen, erizainen eta batez ere farmazialarien eginkizuna funtsezkoa da.

Gako-hitzak: Hypericum perforatum, Santiago belarra, depresioa, medikamentu-elkarrekintzak.

Hypericum perforatum or St. John's wort is a plant that is indicated as a treatment for mild and moderate depression, which is commercialized as a medication and dietary supplement. Its high efficacy has been demonstrated, however, it presents a great deal of interactions with some medicines. Its accessibility is a potential risk that must be considered. For this reason, this article includes the scientific evidence of the interactions that must be taken into account. It is a possible adverse event that people should know, since the social perception that plant origin products are always safe or safer is incorrect. In control and education the role of doctors, nurses and especially chemists is essential.

Key words: Hypericum perforatum, St. John's wort, depression, drug interactions.